Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes

Kavli Affiliate: John Rubenstein | Authors: Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F. Page, Lindsay Liang, Athena R. Ypsilanti, Eirene Markenscoff-Papadimitriou, Matthew W. State, Alex S. Nord, Stephan J. Sanders and John L. R. Rubenstein | Summary: Abstract The authors have withdrawn their manuscript because of uncertainty about an antibody reagent that was […]


Continue.. Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes

Testing the data framework for an AI algorithm in preparation for high data rate X-ray facilities

Kavli Affiliate: Cheng Peng | First 5 Authors: Hongwei Chen, Sathya R. Chitturi, Rajan Plumley, Lingjia Shen, Nathan C. Drucker | Summary: The advent of next-generation X-ray free electron lasers will be capable of delivering X-rays at a repetition rate approaching 1 MHz continuously. This will require the development of data systems to handle experiments […]


Continue.. Testing the data framework for an AI algorithm in preparation for high data rate X-ray facilities

Internal noise promotes heterogeneous synaptic dynamics important for working memory in recurrent neural networks

Kavli Affiliate: Terrence Sejnowski | Authors: Nuttida Rungratsameetaweemana, Robert Kim and Terrence Sejnowski | Summary: Abstract Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neurons perform cognitive tasks. Training such networks to perform tasks that require information maintenance over a brief period […]


Continue.. Internal noise promotes heterogeneous synaptic dynamics important for working memory in recurrent neural networks

DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katherine Bogue, Terrence J Sejnowski and Shyam Srinivasan | Summary: Abstract Epigenetic changes are involved in the onset and progression of cancer, and the detection of DNA methylation signatures may foster the improvement of diagnosis and prognosis. While the emergence of innovative technologies has fostered numerous studies […]


Continue.. DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis

Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon

Kavli Affiliate: Pasko Rakic, Nenad Sestan | Authors: Nicola Micali, Shaojie Ma, Mingfeng Li, Suel-Kee Kim, Xoel Mato-Blanco, Suvimal Sindhu, Jon I. Arellano, Tianliuyun Gao, Alvaro Duque, Gabriel Santpere, Nenad Sestan and Pasko Rakic | Summary: Abstract Early telencephalic development involves patterning of the distinct regions and fate specification of the neural stem cells (NSCs). […]


Continue.. Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon

First results from the JWST Early Release Science Program Q3D: Turbulent times in the life of a $z sim 3$ extremely red quasar revealed by NIRSpec IFU

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Dominika Wylezalek, Andrey Vayner, David S. N. Rupke, Nadia L. Zakamska, Sylvain Veilleux | Summary: Extremely red quasars, with bolometric luminosities exceeding $10^{47}$ erg s$^{-1}$, are a fascinating high-redshift population that is absent in the local universe. They are the best candidates for supermassive black holes accreting […]


Continue.. First results from the JWST Early Release Science Program Q3D: Turbulent times in the life of a $z sim 3$ extremely red quasar revealed by NIRSpec IFU

Moving gravitational wave sources at cosmological distances: Impact on the measurement of the Hubble constant

Kavli Affiliate: Xian Chen | First 5 Authors: Alejandro Torres-Orjuela, Xian Chen, , , | Summary: Standard sirens — gravitational wave (GW) sources with an electromagnetic (EM) counterpart — can be used to measure the Hubble constant directly which should help to ease the existing Hubble tension. However, if the source is moving, a relativistic […]


Continue.. Moving gravitational wave sources at cosmological distances: Impact on the measurement of the Hubble constant