Kavli Affiliate: Mark Vogelsberger | Summary:We present a high-resolution hydrodynamical simulation of the formation and evolution of nuclear structures in a Milky Way-mass galaxy using the SMUGGLE multiphase ISM and stellar feedback model. The system naturally develops a bar of length $approx5$ kpc in isolation, driving sustained gas inflows toward the center that lead to […]
Kavli Affiliate: Joseph Falson | Summary:Accessing surface quantum transport in topological insulators is hampered by residual bulk conduction arising from lattice defects. Here, we demonstrate a novel synthesis pathway for realizing high mobility $β$-Ag$_2$Te thin films where surface transport is dominant. An textitin-situ vacancy engineering step as part of the molecular beam epitaxy growth process […]
Kavli Affiliate: Liedewij Laan | Summary:Multidomain proteins with flexible unstructured sequence regions are abundant in cellular signaling. This protein architecture enables self-assembly into supramolecular structures, but how structured interaction domains and overall protein architecture jointly regulate the assembly size, structure and kinetics remains unclear. Here we use the budding yeast protein Bem1 as a model […]
Kavli Affiliate: Lijing Shao | Summary:Discovery and timing observations of a radio pulsar orbiting around Sagittarius A*, the supermassive black hole (SMBH) in our Galactic Centre (GC), will provide unprecedented opportunities of studying the SMBH spacetime, testing gravity theories, and probing the astrophysical environment in the GC. However, unknown mass distributions might cause timing residuals […]
Kavli Affiliate: Luis Ho | Summary:We present a spectroscopic analysis of 14 little red dots (LRDs) at redshifts $2.2 < z < 6.7$ using NIRSpec/MSA prism and medium-resolution grating observations, aiming to constrain the nuclear gas structure through Balmer emission-line profiles, absorption features, relative line intensities, and continuum properties. We simultaneously decompose the broad, narrow, […]
Kavli Affiliate: Luis Ho | Summary:Balmer absorption lines are increasingly observed in the little red dots (LRDs) discovered by the James Webb Space Telescope, potentially tracing dense circumnuclear gas around rapidly accreting black holes. Motivated by this connection, we search for Balmer absorption using homogeneously analyzed spectra of a representative parent sample of 14,584 low-redshift […]
Kavli Affiliate: Rainer Spurzem | Summary:We want to understand how the combined effect of initial substructure, primordial mass segregation, and primordial binaries affects the dynamical evolution of the cluster, and which one of these features is the most important to agree with observations. Methods. We use Nbody6++GPU to simulate the dynamics of star clusters with […]
Kavli Affiliate: Eiichiro Komatsu | Summary:The Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) is a wide-field, integral-field spectroscopic survey designed to map the large-scale distribution of Lyman-alpha emitting galaxies (LAEs) at 1.88 < z < 3.52 and constrain dark energy at cosmic noon. Using the 10-m Hobby-Eberly Telescope and the Visible Integral-Field Replicable Unit (IFU) Spectrograph, […]
Kavli Affiliate: Kenta Asahina | Authors: Linghao Hu, Pingchuan Ma, Vaibhav Menon, Athira Sethu Madhavan, Kenta Asahina, Lena M. Müller and Adam J. Bowman | Summary: Fluorescence lifetime microscopy is limited by photon throughput, constraining the speed and dynamic range of biological measurements. We demonstrate a compact optical module and fast phasor acquisition methods to […]
Kavli Affiliate: Lily Jan | Authors: Yayu Wang and Lily Yeh Jan | Summary: This protocol describes manual whole-endolysosome patch-clamp recordings from pharmacologically or genetically enlarged endolysosomes in cultured mammalian cells. Steps include vesicle enlargement, fabrication and fire-polishing of high-resistance pipettes, mechanical dissection and isolation of enlarged vesicles, giga-seal formation, and configuration to whole-endolysosome modes. […]