Upregulated SEMA3C in astrocytes contributes to Rett Syndrome phenotypes

Posted by dbos UCSD / Salk

Kavli Affiliate: Nicola Allen | Authors: Krissy A Lyon, Adrien Paumier, Ananya Kandikonda, Andrea Melendez and Nicola J Allen | Summary: Astrocytes support neuronal function during development through secreted proteins, yet how astrocyte-secreted cues are altered in disease states and contribute to neurodevelopmental disorders remains poorly defined. Rett syndrome (RTT) is a regressive neurodevelopmental disorder […]


Continue.. Upregulated SEMA3C in astrocytes contributes to Rett Syndrome phenotypes

BARseq3: a modular system for integrating spatial multi-omics and cellular barcoding in single cells

Posted by dbos Hopkins

Kavli Affiliate: Justus M Kebschull | Authors: Huihui Qi, Manjari M-G Anant, Dylan Z Faltine-Gonzalez, Ruitao Hu, Lai Wei, Christopher D Workman, Caleb Shi, Ishbel Del Rosario and Justus M Kebschull | Summary: Understanding cellular identity requires multimodal measurements in single cells. Cellular barcoding provides powerful tools for recording the properties or history of individual […]


Continue.. BARseq3: a modular system for integrating spatial multi-omics and cellular barcoding in single cells

Lever: Speculative LLM Inference on Smartphones

Posted by klaurent Caltech

Kavli Affiliate: Wei Gao| Summary:Large language models (LLMs) are increasingly needed for interactive mobile applications, but high-quality models exceed the limited DRAM available on smartphones. Flash storage can hold larger models, yet flash-backed inference is slow because autoregressive decoding repeatedly invokes the target model and incurs costly I/O. We observe that speculative decoding is a […]


Continue.. Lever: Speculative LLM Inference on Smartphones