G2L:From Giga-Scale to Cancer-Specific Large-Scale Pathology Foundation Models via Knowledge Distillation

Kavli Affiliate: Hsiao-Mei (Sherry) Cho| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:Recent studies in pathology foundation models have shown that scaling training data, diversifying cancer types, and increasing model size consistently improve their performance. However, giga-scale foundation models, which are trained on hundreds of thousands of slides covering tens of cancer types and […]


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APLOT: Robust Reward Modeling via Adaptive Preference Learning with Optimal Transport

Kavli Affiliate: Zhuo Li | First 5 Authors: Zhuo Li, Zhuo Li, , , | Summary: The reward model (RM) plays a crucial role in aligning Large Language Models (LLMs) with human preferences through Reinforcement Learning, where the Bradley-Terry (BT) objective has been recognized as simple yet powerful, specifically for pairwise preference learning. However, BT-based […]


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Image reconstruction with the JWST Interferometer

Kavli Affiliate: Peter Ford| First 5 Authors: Max Charles, Max Charles, , , | Summary:Flying on board the James Webb Space Telescope (JWST) above Earth’s turbulent atmosphere, the Aperture Masking Interferometer (AMI) on the NIRISS instrument is the highest-resolution infrared interferometer ever placed in space. However, its performance was found to be limited by non-linear […]


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Generalized quantum limits of electrical contact resistance and thermal boundary resistance

Kavli Affiliate: Grace Xing | Summary:The importance of electrical contact resistance and thermal boundary resistance has increased dramatically as devices are scaled to atomic limits. The use of a rich range of materials with various bandstructures (e.g. parabolic, conical), and in geometries exploiting various dimensionalities (e.g. 1D wires, 2D sheets, and 3D bulk) will increase […]


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Co-evolution of Nuclear Star Clusters and Massive Black Holes: Extreme Mass-Ratio Inspirals

Kavli Affiliate: Pau Amaro Seoane | Summary:We explore extreme mass-ratio inspirals (EMRIs) in the co-evolution of massive black holes (MBHs) and nuclear star clusters (NSCs), which host diverse stellar populations across a wide range of masses. The dynamics are simulated self-consistently with GNC, which we have updated to incorporate gravitational wave orbital decay, the loss […]


Continue.. Co-evolution of Nuclear Star Clusters and Massive Black Holes: Extreme Mass-Ratio Inspirals

Co-evolution of Nuclear Star Clusters and Massive Black Holes: Extreme Mass-Ratio Inspirals

Kavli Affiliate: Pau Amaro Seoane | Summary:We explore extreme mass-ratio inspirals (EMRIs) in the co-evolution of massive black holes (MBHs) and nuclear star clusters (NSCs), which host diverse stellar populations across a wide range of masses. The dynamics are simulated self-consistently with GNC, which we have updated to incorporate gravitational wave orbital decay, the loss […]


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Dual Band Receiver Design for the Black Hole Explorer (BHEX) Mission

Kavli Affiliate: Edward Morgan| First 5 Authors: Cheukyu Edward Tong, Cheukyu Edward Tong, , , | Summary:A dual band receiver has been designed for the Black Hole Explorer (BHEX) mission, which is a space Very-Long Baseline Interferometry (VLBI) mission concept, aimed at unveiling the photon ring of black holes. The cryogenic receiver comprises a 228-320 […]


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Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Elizabeth Hillman | Authors: Mary Claire Tuohy, Ping-Chang Kuo, Adrian Chelminski, Eti Muharremi, Claudia DeSantis, Aomeng Cui, Alicia Russo, Danny Jamoul, Elizabeth Hillman, John F Crary, Jui-Hung Jimmy Yen and Dritan Agalliu | Summary: Vascular normalization [stabilization of aberrant angiogenesis […]


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Rearing condition affects behavioral response to cross-modal expectancy violation paradigm in zebra finche

Kavli Affiliate: Sarah Woolley | Authors: Isabella Catalano and Sarah Cushing Woolley | Summary: Interacting in a multimodal world, including recognizing other individuals across multiple sensory modalities, is important for animals who rely on social relationships for survival. Social and sensory experiences shape how multisensory information is processed and integrated; however, we have less understanding […]


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Astrocyte SEMA3C reduction improves Rett Syndrome phenotypes

Kavli Affiliate: Nicola Allen | Authors: Krissy A Lyon, Adrien Paumier, Ananya Kandikonda, Andrea Melendez and Nicola J Allen | Summary: During typical neurodevelopment, astrocytes secrete proteins that support neuronal connectivity. This process is disrupted in Rett Syndrome (RTT), a regressive neurodevelopmental disorder characterized by motor, sensory, and cognitive impairments. While astrocytes typically promote neuron […]


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