Senescence-Linked Fibrosis in the Aging Human Ovary Revealed by p16-Based Histological Profiling and Spatial Transcriptomics

Kavli Affiliate: Denis Wirtz | Authors: Mark A Watson, Pooja Raj Devrukhkar, Natalia F Murad, Fan Wu, Moo J Kim, Hannah Anvari, Uyen Tran, Nicolas Martin, Tommy Tran, Giuliana Zaza, Kevin Schneider, Bikem Soygur, Elisheva D Shanes, Denis Wirtz, MaryEllen G Pavone, Simon Melov, Pei-Hsun Wu, David Furman, Francesca E Duncan and Birgit Schilling | […]


Continue.. Senescence-Linked Fibrosis in the Aging Human Ovary Revealed by p16-Based Histological Profiling and Spatial Transcriptomics

Structured Joint Decomposition (SJD) identifies shared dynamics across collections of biologically related multi-omics data matrices

Kavli Affiliate: Brian Caffo | Authors: Huan Chen, Guangyan Li, Jinrui Liu, Shreyash Sonthalia, Genevieve Stein-OBrien, Luo Xiao, Brian Caffo and Carlo Colantuoni | Summary: It is necessary to develop exploratory tools to learn from the unprecedented volume of high-dimensional multi-omic data currently being produced across the field of biomedicine. We have developed an R […]


Continue.. Structured Joint Decomposition (SJD) identifies shared dynamics across collections of biologically related multi-omics data matrices

The dynamic central environment of NGC 3516 revealed by XRISM

Kavli Affiliate: Erin Kara | Summary:We present a detailed, time-resolved analysis of the Fe K band of the Seyfert 1.5 galaxy NGC 3516 observed with XRISM. The 249 ks observation spanning $sim$310 ks in elapsed time reveals an exceptionally rich and time-variable absorption spectrum. Six distinct absorption components are detected across multiple ionization states, spanning […]


Continue.. The dynamic central environment of NGC 3516 revealed by XRISM

Hot, Photoionized X-ray Gas in Two Luminous Type 2 Quasars: Chandra-HST Evidence for a Wind-Driven Sequence

Kavli Affiliate: Luis Ho | Summary:We present new Chandra/ACIS-S imaging spectroscopy of two luminous type 2 quasars, FIRST J120041.4+314745 ($z$=0.116) and 2MASX J13003807+5454367 ($z$=0.088), and compare their X-ray emission with Hubble Space Telescope [O III]$λ$5007 morphologies and kinematics. Both systems show kiloparsec-scale soft X-ray emission. In FIRST J120041, the X-ray morphology is clumpy and closely […]


Continue.. Hot, Photoionized X-ray Gas in Two Luminous Type 2 Quasars: Chandra-HST Evidence for a Wind-Driven Sequence

JWST TRAPPIST-1 e/b Program: Motivation and first observations

Kavli Affiliate: Sara Seager | Summary:One of the forefront goals in the field of exoplanets is the detection of an atmosphere on a temperate terrestrial exoplanet, and among the best suited systems to do so is TRAPPIST-1. However, JWST transit observations of the TRAPPIST-1 planets show significant contamination from stellar surface features that we are […]


Continue.. JWST TRAPPIST-1 e/b Program: Motivation and first observations

SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

Kavli Affiliate: James Bock | Summary:From 01- to 15-Aug-2025UT, the SPHEREx spacecraft observed interstellar object 3I/ATLAS. Using $R=40-130$ spectrophotometry at $λ=0.7-5$ $μ$m, light curves, spectra, and imaging of ATLAS were obtained. From these, robust detections of water gas emission at $2.7-2.8$ $μ$m and $CO_2$ gas at $4.23-4.27$ $μ$m plus tentative detections of $^13CO_2$ and $CO$ […]


Continue.. SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

Kavli Affiliate: James Bock | Summary:From 01- to 15-Aug-2025 UT, the SPHEREx spacecraft observed interstellar object 3I/ATLAS. Using $R = 40$-$130$ spectrophotometry at $λ= 0.7$-$5μ$m, light curves, spectra, and imaging of 3I were obtained. From these, robust detections of water gas emission at $2.7$-$2.8,μ$m and CO$_2$ gas at $4.23$-$4.27,μ$m plus tentative detections of $^13$CO$_2$ and […]


Continue.. SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

Systematic bias due to eccentricity in parameter estimation for merging binary neutron stars : spinning case

Kavli Affiliate: Hsiao-Mei (Sherry) Cho| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:In our previous work [Phys. Rev. D bf 105. 124022 (2022)], we studied the impact of eccentricity on gravitational-wave parameter estimation for a nonspinning binary neutron star (BNS) system. We here extend the work to a more realistic case by including the […]


Continue.. Systematic bias due to eccentricity in parameter estimation for merging binary neutron stars : spinning case

PICKT: Practical Interlinked Concept Knowledge Tracing for Personalized Learning using Knowledge Map Concept Relations

Kavli Affiliate: Hsiao-Mei (Sherry) Cho| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:With the recent surge in personalized learning, Intelligent Tutoring Systems (ITS) that can accurately track students’ individual knowledge states and provide tailored learning paths based on this information are in demand as an essential task. This paper focuses on the core technology […]


Continue.. PICKT: Practical Interlinked Concept Knowledge Tracing for Personalized Learning using Knowledge Map Concept Relations