Kavli Affiliate: Erich Jarvis | Authors: Larissa S. Arantes, Tom Brown, Diego De Panis, Scott D. Whiting, Erin L. LaCasella, Gabriella A. Carvajal, Adam Kennedy, Deana Edmunds, Blair P. Bentley, Jennifer Balacco, Conor Whelan, Nivesh Jain, Tatiana Tilley, Brian O’Toole, Patrick Traore, Erich D. Jarvis, Oliver Berry, Peter H. Dutton, Lisa M. Komoroske and Camila […]
Kavli Affiliate: Lindsay Baker | Summary:A protein’s structure in the gas phase underpins the interpretation of native mass spectrometry. Yet how fold and conformation respond to dehydration has never been resolved at the residue level, due to the unavailability of a method to image gas-phase proteins at near-atomic resolution. Here, we determine near-atomic-resolution cryoEM structures […]
Kavli Affiliate: Carol Robinson | Summary:Electrospray ion beam deposition (ESIBD) is the intact, chemically selective deposition of molecular ions on surfaces in vacuum. Here, we present a general method and dedicated instrumentation for ESIBD-based cryoEM sample preparation of soluble proteins. Precise control over deposition energy, sample environment, and reproducible growth of thin, homogeneous, vitreous ice […]
Kavli Affiliate: Lindsay Baker | Summary:Soft-landing electrospray ion beam deposition (ESIBD), i.e. the chemically selective, intact deposition of large and complex molecules on surfaces in vacuum, is a well-established sample preparation method for scanning probe microscopy (SPM), where it facilitates the high-resolution imaging of large and complex molecules. Inherited from mass spectrometry, the advantageous properties […]
Kavli Affiliate: Eiichiro Komatsu | Summary:Cosmic birefringence (CB) is the rotation of the photons’ linear polarisation plane during propagation. Such an effect is a tracer of parity-violating extensions of standard electromagnetism and would probe the existence of a new cosmological field acting as dark matter or dark energy. It has become customary to employ cosmic […]
Kavli Affiliate: Zeeshan Ahmed | Summary:Simultaneous or streaming machine translation generates translation while reading the input stream. These systems face a quality/latency trade-off, aiming to achieve high translation quality similar to non-streaming models with minimal latency. We propose an approach that efficiently manages this trade-off. By enhancing a pretrained non-streaming model, which was trained with […]