Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling

Kavli Affiliate: Michael W. Young | Authors: Michael Young, David M Booth, David Smith, Marco Tigano, Gyorgy Hajnoczky and Suresh Joseph | Summary: The activation of IP3 receptor (IP3R) Ca2+ channels generates agonist-mediated Ca2+ signals that regulate a wide range of biological processes. It is therefore surprising that CRISPR induced loss of all three IP3R […]


Continue.. Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling

A Subcortical Feeding Circuit Linking Interoception to Jaw movement

Kavli Affiliate: Jeffrey M. Friedman and Zachary Knight | Authors: Christin Kosse, Jessica Ivanov, Zachary Knight, Kyle Pellegrino and Jeffrey Friedman | Summary: The brain processes an array of stimuli enabling the selection of an appropriate behavioural response but the neural pathways linking interoceptive inputs to outputs for feeding are poorly understood. Here we delineate […]


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DMesh: A Differentiable Representation for General Meshes

Kavli Affiliate: Yi Zhou | First 5 Authors: Sanghyun Son, Matheus Gadelha, Yang Zhou, Zexiang Xu, Ming C. Lin | Summary: We present a differentiable representation, DMesh, for general 3D triangular meshes. DMesh considers both the geometry and connectivity information of a mesh. In our design, we first get a set of convex tetrahedra that […]


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Extracting Geometry and Topology of Orange Pericarps for the Design of Bioinspired Energy Absorbing Materials

Kavli Affiliate: Chiara Daraio | First 5 Authors: Chelsea Fox, Kyle Chen, Micaela Antonini, Tommaso Magrini, Chiara Daraio | Summary: As a result of evolution, many biological materials have developed irregular structures that lead to outstanding mechanical properties, like high stiffness-to-weight ratios and good energy absorption. To reproduce these properties in synthetic materials, biomimicry typically […]


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Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Kavli Affiliate: Erin Kara | First 5 Authors: Minghao Yue, Anna-Christina Eilers, Tonima Tasnim Ananna, Christos Panagiotou, Erin Kara | Summary: Recent {em James Webb Space Telescope (JWST)} observations have revealed a population of compact extragalactic objects at $zgtrsim4$ with red near-infrared colors, which have been dubbed as “Little Red Dots" (LRDs). The spectroscopically-selected LRDs […]


Continue.. Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Kavli Affiliate: Erin Kara | First 5 Authors: Minghao Yue, Anna-Christina Eilers, Tonima Tasnim Annana, Christos Panagiotou, Erin Kara | Summary: Recent {em James Webb Space Telescope (JWST)} observations have revealed a population of compact extragalactic objects at $zgtrsim4$ with red near-infrared colors, which have been dubbed as “Little Red Dots" (LRDs). The spectroscopically-selected LRDs […]


Continue.. Stacking X-ray Observations of “Little Red Dots”: Implications for their AGN Properties

Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene

Kavli Affiliate: Gang Su | First 5 Authors: Ze Liu, Zhi-Fan Zhang, Zhen-Gang Zhu, Gang Su, | Summary: The geometric properties of parameter space are mostly described by Berry curvature and quantum metric, which is the imaginary and real part of quantum geometric tensor, respectively. In this work, we calculate the dressed Berry curvature and […]


Continue.. Effect of disorder on Berry curvature and quantum metric in two-band gapped graphene