Rapid generation of ventral A9-like dopaminergic neurons from patterned iPSCs

Kavli Affiliate: Xin Duan | Authors: Kriti Chaplot, Lin Zhang, Julia Wessman, Miguel Rivera, Zhihui Wang, Fei Wang, Xin Duan, Pamela M. England, Iain C. Clark and Erik M. Ullian | Summary: In vitro modelling of highly vulnerable nigral dopaminergic (DA) neuronal subtypes in Parkinson’s disease (PD), is necessary for studying disease mechanisms. Here, we […]


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Characterising Atomic-Scale Surface Disorder on 2D Materials Using Neutral Atoms

Kavli Affiliate: Ke Wang | First 5 Authors: Chenyang Zhao, Chenyang Zhao, , , | Summary: Two-dimensional (2D) transition metal dichalcogenides (TMDs), such as MoS2, have the potential to be widely used in electronic devices and sensors due to their high carrier mobility and tunable band structure. In 2D TMD devices, surface and interface cleanness […]


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A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects

Kavli Affiliate: Denis Wirtz | Authors: Irfan S Kathiriya, Martin H Dominguez, Kavitha S Rao, Jonathon M. Muncie-Vasic, W. Patrick Devine, Kevin M. Hu, Swetansu K Hota, Bayardo I Garay, Diego Quintero, Piyush Goyal, Megan N Matthews, Reuben Thomas, Tatyana Sukonnik, Dario Miguel-Perez, Sarah Winchester, Emily F Brower, André Forjaz, Pei-Hsun Wu, Denis Wirtz, Ashley […]


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SLAy-ing oversplitting errors in high-density electrophysiology spike sorting

Kavli Affiliate: Adam S. Charles and Kathleen Cullen | Authors: Sai Koukuntla, Tate DeWeese, Alexandra Cheng, Robyn Mildren, Aamna Lawrence, Austin R Graves, Kathleen E Cullen, Jennifer Colonell, Timothy D Harris and Adam S Charles | Summary: The growing channel count of silicon probes has substantially increased the number of neurons recorded in electrophysiology (ephys) […]


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Small Cancellation for Random Branched Covers of Groups

Kavli Affiliate: Hsiao-Mei (Sherry) Cho| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:We construct a random model for an $n$-fold branched cover of a finite acceptable $2$-complex $X$. This includes presentation $2$-complexes for finitely presented groups satisfying some mild conditions. For any $λ>0$, we show that as $n$ goes to infinity, a random branched […]


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Advancing AI Challenges for the United States Department of the Air Force

Kavli Affiliate: Scott A. Hughes| First 5 Authors: Christian Prothmann, Christian Prothmann, , , | Summary:The DAF-MIT AI Accelerator is a collaboration between the United States Department of the Air Force (DAF) and the Massachusetts Institute of Technology (MIT). This program pioneers fundamental advances in artificial intelligence (AI) to expand the competitive advantage of the […]


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The Advanced X-ray Imaging Satellite (AXIS) Community Science Book

Kavli Affiliate: Erin Kara | Summary:The AXIS Community Science Book represents the collective effort of 592 scientists worldwide to define the transformative science enabled by the Advanced X-ray Imaging Satellite (AXIS), a next-generation X-ray mission selected by NASA’s Astrophysics Probe Program for Phase A study. AXIS will advance the legacy of high-angular-resolution X-ray astronomy with […]


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The Advanced X-ray Imaging Satellite Community Science Book

Kavli Affiliate: Claudio Ricci| First 5 Authors: Michael Koss, Michael Koss, , , | Summary:The AXIS Community Science Book represents the collective effort of more than 500 scientists worldwide to define the transformative science enabled by the Advanced X-ray Imaging Satellite (AXIS), a next-generation X-ray mission selected by NASA’s Astrophysics Probe Program for Phase A […]


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Impact of Alzheimer’s disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus

Kavli Affiliate: Keri Martinowich | Authors: Bernard Mulvey, Heena R Divecha, Madhavi Tippani, Svitlana V Bach, Rahul Bharadwaj, Ishbel Del Rosario, Sarah E Maguire, Ryan A Miller, Aaron J Salisbury, Atharv Chandra, Beau A Oster, Kelsey D Montgomery, Sang Ho Kwon, Haya A Algrain, Alexis R Papariello, Louise A Huuki-Myers, Joel E Kleinman, Leonardo Collado-Torres, […]


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BOOM and Babamul: a real-time, multi-survey, optical alert broker system operating at scale

Kavli Affiliate: Peter Graham| First 5 Authors: Theophile Jegou du Laz, Theophile Jegou du Laz, , , | Summary:With the arrival of ever higher throughput wide-field surveys and a multitude of multi-messenger and multi-wavelength instruments to complement them, software capable of harnessing these associated data streams is urgently required. To meet these needs, a number […]


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