Single-Molecule Structure and Topology of Kinetoplast DNA Networks

Kavli Affiliate: Cees Dekker | Summary:The Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked 2.5 kb-long DNA minicircles found in certain parasites called Trypanosomes. Understanding the self-assembly and replication of this structure are not only major open questions in biology but can also inform the design of synthetic topological materials. Here we […]


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The Cosmic Ultraviolet Baryon Survey (CUBS) V: On the Thermodynamic Properties of the Cool Circumgalactic Medium at $z < 1$

Kavli Affiliate: Robert A. Simcoe | First 5 Authors: Zhijie Qu, Hsiao-Wen Chen, Gwen C. Rudie, Fakhri S. Zahedy, Sean D. Johnson | Summary: This paper presents a systematic study of the photoionization and thermodynamic properties of the cool circumgalactic medium (CGM) as traced by rest-frame ultraviolet absorption lines around 26 galaxies at redshift $zlesssim1$. […]


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A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

Kavli Affiliate: Seth Blackshaw | Authors: Marysia Placzek, Kavitha Chinnaiya, Sarah Burbridge, Aragorn Jones, Dong Won Kim, Elsie Place, Elizabeth Manning, Ian Groves, Changyu Sun, Matthew Towers and Seth Blackshaw | Summary: Abstract The tuberal hypothalamus houses several major hypothalamic nuclei, dozens of transcriptionally distinct cell types, and clinically relevant cell populations implicated in obesity […]


Continue.. A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus