A Minimal Mechanosensing Model Predicts Keratocyte Evolution on Flexible Substrates

Kavli Affiliate: G. Ravichandran |Summary:A mathematical model is proposed for shape evolution and locomotion of fish epidermal keratocytes on elastic substrates. The model is based on mechanosensing concepts: cells apply contractile forces onto the elastic substrate, while cell shape evolution depends locally on the substrate stress generated by themselves or external mechanical stimuli acting on […]


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